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Madrigal Pharmaceuticals, Inc. (MDGL)

Undervalued
HealthcareBiotechnologyUnited States

Fundamental

28

Price

$503.96

Market Cap

$11.64B

Part 1 · What the company is worth

Overview

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

No editorial profile for this company yet

Direct competitors

Who this company fights with for the same customers

No editorial profile for this company yet

No competitor list for this company yet.

Balance Sheet & Liquidity

Revenue

$1.28B

Trailing 12 months (through 6/30/2026)

Net Income

$-325M

Trailing 12 months (through 6/30/2026)

Free Cash Flow

$-190M

Total Equity

$603M

Total Liabilities

$657M

Current Ratio

3.20

Interest Coverage

10.24

Debt/EBITDA

-

Earnings Per Share

Revenue & Net Income

Free Cash Flow

Income Breakdown

Historical statement

Margins over time

Debt over time

How heavy the debt is

Growth grid

Growth — Revenue

Fair Value Estimation

General caseUndervalued

Fair Value

$682.11

Current Price

$503.96

Margin of Safety

+26.1%

Fair Value Range

$648.01 - $716.22

Spread across the valuation methods used, not a statistically calibrated confidence interval.

Estimation Methods

Analyst price target:$682.11
Discounted cash flow (DCF):Not enough data to compute it
Earnings multiple (P/E):Not enough data to compute it
Graham growth formula:Not enough data to compute it
Earnings power value (EPV):Not enough data to compute it
Justified P/B:Not enough data to compute it
Dividend discount (Gordon):Not enough data to compute it
P/FFO, funds from operations:Not enough data to compute it
Mid-cycle earnings:Not enough data to compute it
Revenue multiple:$173.56
Analyst Consensus:Strong Buy (22B / 2H / 0S)
Last Earnings Surprise:+23.96%

Valuation Metrics

P/E Ratio

-

ROE

-47.8%

P/B Ratio

22.23

P/FCF

-

Gross Margin

-

ROIC

-29.3%

Profitability Radar

Value Creation (Economic Moat)

ROIC

-29.3%

WACC

7.9%

ROIC − WACC

-37.2 pp

ROIC is below the cost of capital — the company is destroying value for every dollar invested.

Fundamental Analysis Criteria

Passed (7)

  • Price CAGR 42.47%
  • Debt/Equity ratio
  • Current Ratio
  • Interest Coverage
  • Low reliance on intangibles
  • Analyst Consensus 92% Buy
  • Net Margin Trend -25.3% vs -54.7%

Failed (11)

  • EPS shows upward trend
  • ROIC -29.3%
  • P/B Ratio 22.23
  • Operating Margin -25.1%
  • Positive Free Cash Flow
  • Return on Tangible Assets
  • DCF valuation (Unknown)
  • ROE -56.6%
  • Earnings Surprise avg -90.7%
  • Share Dilution 5.5%
  • Piotroski F-Score 3/9

Unavailable (9)

  • Gross Margin NaN%
  • P/FCF NaN
  • Dividend Payout NaN%
  • CapEx intensity
  • Debt/EBITDA
  • Price below Graham Number
  • Revenue Growth 5Y (Finnhub)
  • PEG Ratio (need PE > 0 and growth > 0)
  • Earnings Quality (OCF/Net Income)

Piotroski F-Score

3/9

Serious financial concerns

score
criteria

Earnings Quality

-

Low quality: investigate accounting

Share Dilution

5.5%

Issuing new shares, diluting ownership

Institutional Holdings

Governance

Executive Team

NameTitleAge
Mr. William J. SiboldCEO, President & Director59
Dr. Rebecca A. Taub M.D.Founder, Senior Scientific & Medical Advisor and Director73
Ms. Mardi C. DierExecutive VP & CFO61
Ms. Shannon KelleyExecutive VP, Chief Legal Officer & Corporate Secretary50
Ms. Carole HuntsmanExecutive VP & Chief Commercial Officer60
Dr. David Soergel M.D.Executive VP & Chief Medical Officer57
Mr. Mark UnderwoodExecutive Vice President of Business Planning & Operations-
Ms. Rita ThakkarSenior VP & Chief Accounting Officer51
Mr. Ronald FilippoExecutive VP & Chief Information Officer-
Ms. Tina E. VenturaChief Investor Relations Officer-

Audit Risk

2

Board Risk

3

Compensation Risk

5

Shareholder Rights Risk

8

Part 2 · The price and when to enter

This part won't tell you whether the company is worth owning: it helps you choose when to buy it, once the fundamentals have convinced you. Inside: technical analysis, potential, historical drawdowns, gamma exposure.

Documents

  • Annual Report (10-K)

    A yearly overview of the business, its financial results, and the risks it faces.

    Filed on 2026-02-19

    View document
  • Quarterly Report (10-Q)

    A snapshot of financial performance for the most recent three-month period.

    Filed on 2026-07-30

    View document
  • Current Report (8-K)

    An announcement of a major event, such as a leadership change or big news.

    Filed on 2026-08-12

    View document

via SEC EDGAR

Income History

via SEC EDGAR

Latest News

Recent headlines for MDGL, sourced from Markets Gazette.

  • 5/6/2026NEUTRAL
    Full Transcript: Madrigal Pharmaceuticals Q1 2026 Earnings Call

    Madrigal Pharmaceuticals Inc. held its Q1 2026 earnings call on May 6, 2026. While the transcript is available, the provided snippet does not contain specific financial results, forward-looking statements, or significant operational updates that would directly impact the company's stock valuation. Investors seeking to assess the company's performance and outlook should refer to the full earnings report and call transcript for detailed financial figures, management commentary on key business drivers, and any guidance provided for future periods. Without this detailed information, a definitive market impact cannot be determined.

  • 3/17/2026POSITIVE
    This Biotech Attracted a $181 Million Investment During a Staggering 1,300% Stock Rally

    Madrigal Pharmaceuticals, a clinical-stage biotech focused on NASH, obesity, and metabolic diseases, has seen its stock surge by an astonishing 1,300%. This remarkable rally has been further bolstered by a significant $181 million investment, underscoring strong investor confidence in the company's therapeutic pipeline. The substantial capital infusion is expected to accelerate clinical development and research efforts, potentially bringing its innovative small-molecule therapies closer to market approval. For investors, this dual validation of strong market performance and external financial backing signals robust growth prospects.

  • 2/23/2026NEUTRAL
    Madrigal (MDGL) Q4 2025 Earnings Call Transcript

    Madrigal Pharmaceuticals has released the transcript of its fourth-quarter 2025 earnings conference call. While the news itself is informational, the document is a crucial resource for investors. Analysts and shareholders can now scrutinize the management's detailed commentary on financial performance, drug pipeline progress, and the strategic outlook for the future. The question-and-answer session will be of particular interest, as it often reveals nuances and details not found in official press releases. The availability of this comprehensive documentation allows for a deeper analysis, but does not in itself provide a directional signal until its contents are fully digested by the market.

via Markets Gazette