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Exelixis, Inc. (EXEL)

Unterbewertet
HealthcareBiotechnologyUnited States

Fundamental

82

Kurs

$58.73

Marktkapitalisierung

$14.36B

Teil 1 · Was das Unternehmen wert ist

Übersicht

Exelixis is a biotechnology company whose commercial business rests almost entirely on one molecule, cabozantinib, sold in the US under the brand Cabometyx for kidney and other cancers. Outside the US, partners Ipsen and Takeda sell the same molecule under their own arrangements and pay Exelixis a royalty. The cash generated funds a pipeline of experimental cancer therapies the company hopes will eventually reduce its dependence on this single drug.

Wie das Geld verdient wird

Net product revenue is booked when US specialty distributors and pharmacies purchase Cabometyx and the smaller legacy drug Cometriq from Exelixis. Collaboration revenue is the royalty Exelixis earns as a percentage of Cabometyx sales made outside the US by Ipsen and Takeda, plus occasional milestone and license payments under those partnership agreements. Because one molecule drives both lines, group revenue effectively tracks the worldwide commercial performance of cabozantinib rather than a diversified drug portfolio.

Umsatz nach Segment

Net Product Revenue91.5%

US sales of Cabometyx and Cometriq, both built on the cabozantinib molecule, sold through specialty distributors and pharmacies.

Collaboration Revenue8.5%

Royalties on ex-US cabozantinib sales by partners Ipsen and Takeda, plus milestone and license payments under those agreements.

Wettbewerbsvorteil

Patente und Lizenzen · Schmal

Cabometyx is protected by composition-of-matter and formulation patents that block direct generic copies today, and that protection is real. But it is time-limited and narrow rather than broad: Exelixis has already settled patent litigation setting a start date for generic entry in 2031, and the company depends on this one molecule rather than a wide portfolio of protected products.

Was die Nachfrage antreibt

Defensiv

Cabometyx treats cancer, a need that does not go away when the economy weakens, so prescription demand is largely insulated from the broader business cycle. The bigger swing factors are clinical and regulatory instead: approval in new cancer types, competition from rival oncology drugs, and treatment guideline changes move volumes far more than consumer spending patterns do.

Wichtigste Risiken

  • Reliance on a single molecule — The great majority of revenue comes from cabozantinib, sold as Cabometyx; the company's growth is dependent on the continued commercial success of this one franchise across its approved and future indications.
  • Patent expiration and generic entry — Settlement agreements set generic versions of Cabometyx to enter the US market starting in 2031; once that happens, pricing pressure from generics and competing branded drugs is expected to pressure sales.
  • Concentration among specialty distributors — Nearly all product reaches patients through a small number of specialty distributors and pharmacies; a disruption to, or renegotiation with, any one of them could affect a meaningful share of sales.
  • Dependence on collaboration partners outside the US — Essentially all revenue generated outside the United States depends on Ipsen and Takeda commercializing cabozantinib effectively in their territories; a change in either partner's commercial effort directly reduces Exelixis's royalty income.

Die Argumente dafür

Buyers argue that Cabometyx still has years of patent-protected growth ahead as it expands into new cancer indications, that the cash it generates is funding a broad pipeline that could reduce single-drug dependence over time, and that ninth consecutive year of profitability shows the franchise can fund its own future rather than needing dilutive financing.

Die Argumente dagegen

Sellers fear that a company this dependent on one molecule has little room for error if a competing drug, a safety signal or slower-than-expected pipeline progress emerges, that the 2031 generic entry date sets a visible expiration on the current growth story, and that royalty income outside the US leaves Exelixis reliant on partners it does not control.

Written by the editors, published on 18. August 2026

Direct competitors

Who this company fights with for the same customers

Compare

Generated on 18. September 2026 with claude-haiku-4-5 — shared with all users

P/E: 116.2Score: 63Market cap: $366.84B

Merck's Keytruda-plus-Lenvima regimen and its oral HIF-2α inhibitor Welireg compete directly with Cabometyx for the same advanced kidney-cancer patients in the United States and Europe.

P/E: 13.7Score: 72Market cap: $130.49B

Bristol-Myers Squibb's Opdivo plus Yervoy is a first-line alternative for the same advanced kidney-cancer and liver-cancer patients, even though Opdivo is also partnered with Cabometyx in another regimen.

P/E: 37.5Score: 72Market cap: $163.69B

Pfizer sells Inlyta and Sutent, the kinase inhibitors that Cabometyx has to displace prescription by prescription in advanced renal cell carcinoma.

P/E: 24.6Score: 61Market cap: $255.21B

AstraZeneca's Imfinzi plus Imjudo competes for the first-line advanced liver-cancer patients that Cabometyx targets in its second-largest indication.

Eisai Co., Ltd. (エーザイ株式会社)4523.T

Eisai's Lenvima is the other oral kinase inhibitor prescribed in advanced kidney cancer, liver cancer and differentiated thyroid cancer — the same three indications that carry Cabometyx.

Bilanz & Liquidität

Umsatz

$2.44B

Letzte 12 Monate (bis 3.7.2026)

Nettogewinn

$861M

Letzte 12 Monate (bis 3.7.2026)

Freier Cashflow

$876M

Gesamtes Eigenkapital

$2.16B

Gesamtverbindlichkeiten

$683M

Current Ratio

3.46

Zinsdeckungsgrad

-

Schulden/EBITDA

0.18

Gewinn je Aktie

Umsatz & Nettogewinn

Freier Cashflow

Ertragsaufschlüsselung

Historische Aufstellung

Margen im Zeitverlauf

Verschuldung im Zeitverlauf

Wie schwer die Schulden wiegen

Wachstumsraster

Wachstum — Umsatz

Innerer-Wert-Schätzung

Allgemeiner FallUnterbewertet

Innerer Wert

$104.73

Aktueller Kurs

$58.73

Sicherheitsmarge

+43.9%

Innerer-Wert-Spanne

$68.07 - $141.38

Streubreite zwischen den verwendeten Bewertungsmethoden, kein statistisch kalibriertes Konfidenzintervall.

Bewertungsmethoden

Kursziel der Analysten:$53.69
Diskontierter Cashflow (DCF):$230.77
Gewinnmultiplikator (P/E):$49.67
Graham-Wachstumsformel:$163.71
Ertragskraftwert (EPV):$36.94
Gerechtfertigtes P/B:$59.87
Dividendendiskontierung (Gordon):Nicht genügend Daten zur Berechnung
P/FFO, Funds from Operations:$52.41
Gewinn im Zyklusmittel:$18.07
Umsatzmultiplikator:$36.96
Analystenkonsens:Kaufen (12B / 14H / 1S)
Letzte Gewinnüberraschung:+2.28%

Bewertungskennzahlen

P/E-Verhältnis

18.31

ROE

36.2%

P/B-Verhältnis

7.85

P/FCF

12.34

Bruttomarge

96.5%

ROIC

36.0%

Rentabilitäts-Radar

Wertschöpfung (Wettbewerbsvorteil)

ROIC

36.0%

WACC

7.9%

ROIC − WACC

+28.1 pp

Der ROIC übersteigt die Kapitalkosten: Das Unternehmen schafft Wert für die Aktionäre.

Fundamentalanalyse-Kriterien

Bestanden (21)

  • EPS shows upward trend
  • Price CAGR 14.30%
  • ROIC 36.0%
  • Gross Margin 96.5%
  • P/FCF 12.34
  • Debt/Equity ratio
  • Operating Margin 39.9%
  • Positive Free Cash Flow
  • CapEx intensity
  • Current Ratio
  • Debt/EBITDA
  • Return on Tangible Assets
  • Low reliance on intangibles
  • ROE 42.5%
  • Revenue Growth 5Y 10.1%
  • Earnings Surprise avg 7.2%
  • PEG Ratio 0.53
  • Earnings Quality (OCF/NI) 1.38
  • Share Dilution -5.0%
  • Net Margin Trend 35.3% vs 27.0%
  • Piotroski F-Score 6/9

Nicht bestanden (4)

  • P/B Ratio 7.85
  • Price below Graham Number
  • DCF valuation (Overvalued)
  • Analyst Consensus 44% Buy

Nicht verfügbar (2)

  • Dividend Payout NaN%
  • Interest Coverage

Piotroski F-Score

6/9

Gemischte Signale: Einige Bereiche bedürfen Aufmerksamkeit

score
criteria

Gewinnqualität

1.38

Hohe Qualität: Gewinne durch Cashflow gedeckt

Aktienverwässerung

-5.0%

Aktienrückkäufe. Aktionärsfreundlich

Institutionelle Beteiligungen

Unternehmensführung

Führungsteam

NamePositionAlter
Dr. Stelios Papadopoulos Ph.D.Co-Founder & Independent Chair of the Board77
Dr. Michael M. Morrissey Ph.D.CEO, President & Director64
Mr. Christopher J. SennerExecutive VP & CFO57
Dr. Brenda J. Hefti J.D., Ph.D.Senior VP & General Counsel51
Dr. Dana T. Aftab Ph.D.Executive Vice President of Research & Development61
Mr. Patrick Joseph Haley M.B.A.Executive Vice President of Commercial49
Dr. William Berg M.D.Senior Vice President of Medical Affairs-
Dr. Stefan Krauss Ph.D.VP & Head of Business Development-
Mr. Andrew Ross PetersSenior Vice President of Strategy-
Ms. Deborah Burke CPASenior VP of Finance & Controller69

Prüfungsrisiko

5

Vorstandsrisiko

1

Vergütungsrisiko

4

Aktionärsrechterisiko

4

Teil 2 · Der Preis und der Einstiegszeitpunkt

Dieser Teil sagt nicht, ob das Unternehmen etwas taugt: Er hilft bei der Wahl des Kaufzeitpunkts, nachdem die Fundamentaldaten überzeugt haben. Enthalten: technische Analyse, Potenzial, historische Drawdowns, Gamma-Exposure.

Dokumente

  • Jahresbericht (10-K)

    Ein jährlicher Überblick über das Geschäft, die Finanzergebnisse und die Risiken des Unternehmens.

    Eingereicht am 2026-02-10

    Dokument ansehen
  • Quartalsbericht (10-Q)

    Ein Update zur finanziellen Entwicklung der letzten drei Monate.

    Eingereicht am 2026-08-05

    Dokument ansehen
  • Ad-hoc-Meldung (8-K)

    Eine Mitteilung über ein wichtiges Ereignis, etwa einen Führungswechsel oder eine bedeutende Ankündigung.

    Eingereicht am 2026-09-11

    Dokument ansehen

via SEC EDGAR

Ertragshistorie

via SEC EDGAR

Latest News

Recent headlines for EXEL, sourced from Markets Gazette.

  • 2/28/2026POSITIVE
    3 Reasons Exelixis Stock Could Deliver Market‑Beating Returns Over the Next Decade

    U.S.-based biotech firm Exelixis Inc. is poised to deliver market-beating returns over the next decade, positioning itself as a key player in the oncology pharmaceutical sector. The company specializes in developing innovative cancer therapies through a diversified approach, encompassing small molecules, antibody-drug conjugates, and other biotherapeutics. This strategic focus on advanced technological platforms and a robust pipeline indicates a strong foundation for future growth. Investors should closely monitor Exelixis, as its capacity for innovation in cancer treatment could translate into substantial stock value appreciation, making it an attractive opportunity for those seeking long-term exposure to the biotech sector.

  • 2/20/2026POSITIVE
    Exelixis: The Cash‑Generating Biotech That I Think Deserves a Closer Look in 2026

    Exelixis Inc. is a cash-generating biotech company worth a closer look for 2026. The stock is coming off a strong year, indicating a positive trajectory and future growth potential that could appeal to investors.

via Markets Gazette